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Orforglipron Capsules, lyophilized research peptide vial, Eppix Labs
Chemical StructureOrforglipron Capsules chemical structure
Latest COA

Orforglipron Capsules6mgpercapsule/singlebottle-packof60

Batch
ORFO-CA-26I-01
Tested by
Janoshik
Tested on
2026-09-17
Added
2026-10-03
Avg Mass6.77 mg
Verify on Janoshik
Out of StockCapsule
BatchORFO-CA-26I-01

Orforglipron Capsules

Orforglipron Capsules USA — Capsules

Oral GLP-1 Receptor Agonist

Orforglipron is a synthetic, non-peptide small molecule studied in research as an orally available agonist of the glucagon-like peptide-1 (GLP-1) receptor.

$119.99USD

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Purity VerifiedLab TestedSecure
Research Use Only

This product is intended strictly for laboratory research use within the United States. It is not approved by the FDA for the diagnosis, treatment, cure, or prevention of any disease. Not for human or veterinary use.

By purchasing, you confirm the material will be used solely for lawful research purposes in accordance with applicable U.S. federal, state, and local regulations.

Orforglipron is a synthetic, non-peptide small molecule studied in research as an orally available agonist of the glucagon-like peptide-1 (GLP-1) receptor.

Laboratory and clinical investigations have examined its receptor-binding behavior and downstream metabolic signaling within controlled experimental frameworks.

Purity

Third-party tested for purity, ID, quantity.

Coming Soon

The certificate of analysis for this lot is being finalised and will be published here as soon as the lab returns it.

Chemical Structure
Chemical structure diagram
Compound Properties
CAS Number2212020-52-3
Molecular FormulaC48H48F2N10O5
Molecular Weight883.0 g/mol
PubChem CID137319706

Overview

Orforglipron (LY3502970) is a non-peptide GLP-1 receptor agonist characterized for oral bioavailability — a property that distinguishes it from peptide-based incretin analogues that require injection. Research has focused on its selective activation of the GLP-1 receptor and the resulting effects on metabolic signaling pathways.

In controlled studies it has been evaluated for receptor pharmacology, glycemic regulation, and body-weight endpoints under structured experimental conditions.

History

Orforglipron emerged from medicinal-chemistry programs seeking small-molecule alternatives to peptide GLP-1 receptor agonists. Its non-peptide scaffold was designed to retain receptor agonism while enabling oral dosing.

Subsequent phase 1–3 clinical research has characterized its pharmacological profile in type 2 diabetes and obesity research populations.

Key Research Areas

Investigations into orforglipron focus on GLP-1 receptor activation models and incretin-pathway metabolic regulation. Research frameworks evaluate receptor-binding selectivity, glycemic endpoints, and body-weight outcomes under controlled clinical and preclinical conditions.

2 of the 4 areas below are addressed directly by a paper cited on this page.

GLP-1 receptor activation models

Addressed on this page by Rosenstock 2025, Wharton 2025, Sloop 2024. Each is linked to its source record in the references below, so what was measured — and in what system — can be read rather than taken on trust.

Incretin-pathway metabolic research

No paper cited on this page reports on incretin or metabolic. This heading marks where Orforglipron Capsules is discussed in the category rather than a question the cited literature answers, and it is worth knowing which of these areas has work behind it and which does not.

Oral small-molecule agonist pharmacology

Addressed on this page by Rosenstock 2025, Wharton 2025. Each is linked to its source record in the references below, so what was measured — and in what system — can be read rather than taken on trust.

Glycemic and body-weight endpoint studies

No paper cited on this page reports on glycemic, body or weight. This heading marks where Orforglipron Capsules is discussed in the category rather than a question the cited literature answers, and it is worth knowing which of these areas has work behind it and which does not.

The references section of this page cites 3 primary papers published between 2024 and 2025 — a thin record. Every citation is linked to its PubMed or DOI record so it can be read rather than taken on trust, and the summaries above describe what those papers report rather than what the compound is claimed to do.

Orforglipron Capsules is frequently listed as a peptide by suppliers in this market. It is not one. The structure published on this page is the compound's actual chemistry, and research on it should be read against its own class rather than against peptide literature.

Research compounds attract claims that outrun their evidence. Below are the ones most often encountered for Orforglipron Capsules, set against what the papers cited on this page actually report. Where the record is thin or contested, that is stated rather than smoothed over.

Also called

Orforglipron Capsules is also referred to as orfo, the oral GLP-1.

Preclinical only

Orforglipron Capsules is commonly described online in connection with weight loss, appetite suppression and fat reduction. In the research literature the same compound is filed under GLP-1 receptor activation models, incretin-pathway metabolic research and oral small-molecule agonist pharmacology.

The 3 papers cited on this page, published between 2024 and 2025 describe laboratory and animal work. None reports a controlled trial in humans. Findings in cell culture or in a rodent model describe what happened in that system; they do not establish that the same occurs in humans, and this compound is not approved for human use.

Nothing above is a statement of what this material does. It is a summary of what has been published and what has not. Eppix Labs supplies research materials only and provides no dosing, administration or protocol guidance.

Verification for Orforglipron Capsules is per lot, not per product. The current 6mgpercapsule/singlebottle-packof60 lot ORFO-CA-26I-01 returned 6.77 mg measured, assayed by Janoshik. Those figures are the laboratory's, published in full rather than reduced to a badge.

The lot code printed on the bottle matches the code on the certificate for Orforglipron Capsules. Matching the two is what confirms the unit in hand came from the batch that was tested — a certificate not tied to a lot code proves nothing about any particular unit.

Researchers who buy Orforglipron Capsules in the United States through Eppix Labs receive the lot described by the certificate above: the code printed on the vial label is the code on the certificate, and both are searchable on the batch verification page.

Verify a batch code →

Storage
Cool, dry, away from direct light
Humidity
Keep sealed; capsule shells are hygroscopic
Reconstitution
Not applicable — supplied pre-measured
Format
Oral capsule

Orforglipron Capsules is supplied in capsule form, which removes the reconstitution step entirely: there is no vehicle to add, no reconstitution volume to record and no post-reconstitution stability window to track. What that leaves a laboratory to control is storage — capsule shells draw moisture from the air, so the container should be kept sealed and dry rather than decanted into an open vessel.

Because the material is already at its labelled quantity per capsule, batch verification carries more weight in this format than it does for powder: there is no point at which the researcher independently confirms mass by weighing. The measured content published for each lot is the figure that answers that question.

Reconstitution calculator →

Included
  • 1 × sealed capsule bottle (6mg per capsule / Single Bottle - Pack of 60), batch-labelled
  • Batch documentation for the lot shipped, once its certificate is published
  • Discreet outer packaging with no product names on the exterior
  • FedEx, tracked, typically 1–3 business days domestically
Not included
  • Laboratory consumables of any kind
  • Dosing, administration or protocol guidance of any kind

No. Eppix Labs products are supplied exclusively for laboratory research. We do not provide dosing, administration, or usage guidance.

Each unit contains the labeled quantity of orforglipron. Independent third-party analysis verifies purity, identity, and net content per batch.

The unit contains only the research compound. Any laboratory materials required for reconstitution or experimental procedures must be sourced separately.

Duration depends entirely on research design, storage conditions, and laboratory protocol.

Rosenstock, J. et al.(2025)

Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes

PubMed
Wharton, S. et al.(2025)

Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment

PubMed
Sloop, KW. et al.(2024)

The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron

PubMed

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